A bufo ceremony is a ritual or guided psychedelic experience involving 5-MeO-DMT, a very powerful psychedelic compound. “Bufo” commonly refers to the Sonoran Desert toad (Incilius alvarius), whose venom can contain 5-MeO-DMT, although many modern ceremonies use synthetic 5-MeO-DMT instead.

Typically, a ceremony involves:

• A facilitator or guide who prepares and supervises the participant.
• Inhalation of 5-MeO-DMT, producing an extremely intense experience that usually lasts minutes rather than hours.
• Participants may experience profound changes in perception, sense of self, emotions, or consciousness; some describe a feeling of “ego dissolution” or spiritual unity.
• A period afterward for resting and sometimes discussing or “integrating” the experience.

Important: 5-MeO-DMT is substantially more intense than many commonly known psychedelics. It can cause panic, vomiting, loss of physical coordination, unconsciousness, and potentially dangerous interactions with certain medications or other drugs. The safety of a ceremony depends heavily on screening, supervision, substance identification, and the setting.

If you’re considering attending one, I can also explain what actually happens during a bufo ceremony, the risks, and how to recognize an unsafe facilitator.